Natural Gums and Mucilages: A Review on Multifaceted Excipients in Pharmaceutical Science and Research

نویسندگان

  • Rohit Rajendra Bhosale
  • Riyaz Ali M. Osmani
  • Afrasim Moin
چکیده

The application of natural polysaccharides in novel drug delivery systems to deliver the bioactive agents has been hampered by the synthetic polymers. The main benefits of the natural polysaccharides are their being biodegradable, biocompatible, non-toxic, richly available and less expensive. Because of the advances in drug delivery technology, natural polysaccharides are included in novel drug delivery to fulfill multitask functions and in some cases directly or indirectly control the extent and/or rate of drug release. Substantial research efforts have been directed towards developing safe and efficient natural based polysaccharide particulate drug delivery systems. The present review outlines the natural based polysaccharides, natural gums and mucilages and their isolation, purification, standardization and characterization characteristics along with their applications are covered. Also this review covers fabrication techniques for natural polysaccharide based particulate drug delivery systems, specifically micro and nanoparticle drug delivery systems with their characterization techniques and applications are discussed.

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تاریخ انتشار 2014